Researchers explored the impact of hepatopancreaticoduodenectomy (HPD), a radical surgery for biliary carcinoma, on survival in patients with widespread cancer. Of the 54 patients who underwent HPD, 89% achieved R0 resection, significantly improving survival with a median of 36.9 months. Pathological portal vein involvement was identified as an independent prognostic factor. Those with peripancreatic lymph node metastasis or portal vein invasion might reconsider HPD as their first choice. This study offers insights to redefine surgical indications for advanced biliary malignancy.
Journal Article by Yoshimi Y, Noji T (…) Hirano S et 11 al. in Ann Surg Oncol
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