Histopathologic Insights into Median Arcuate Ligament Syndrome

In a breakthrough study, researchers introduced the first histopathologic grading system for Median Arcuate Ligament Syndrome (MALS). Examining specimens from 36 patients who underwent robotic MALS surgery, the team identified unique nerve and lipogranuloma findings. Histopathologic abnormalities correlated with postoperative improvement, supporting nerve compression and inflammation as key contributors to MALS pain. The study advocates for celiac ganglia resection to alleviate symptoms and emphasizes ongoing histopathologic analysis for a deeper understanding of MALS.