Cirrhosis Severity Shapes Challenges and Outcomes in Minimally Invasive Liver Resections

Examining 2534 cases across 58 global centers, this study dissected the impact of cirrhosis on minimally invasive major hepatectomies (MIMH) for liver malignancies. Child-Pugh A cirrhosis correlated with increased morbidity and extended hospital stays. Child-Pugh B cirrhotics faced higher transfusion rates and prolonged hospitalization. However, matching cirrhotics with and without portal hypertension revealed no significant outcome differences. Notably, cirrhosis severity impacted MIMH difficulty and outcomes, signaling a need for nuanced difficulty scoring systems integrating cirrhosis variables.