Tissue Adhesives and Sealants Show Promise in Preventing Anastomotic Leakage

For colorectal cancer patients, anastomotic leakage (AL) poses a significant risk despite efforts to reduce it. A scoping review of seven studies explored the role of tissue adhesives and sealants in preventing AL-related complications. Five studies reported reduced AL rates in the intervention group, suggesting a positive impact. While secondary outcomes were minimally reported, the findings highlight the potential benefits of adhesives and sealants in colorectal anastomosis healing. However, the sparse literature underscores the need for further clinical studies.