Pancreatic Cancer Diagnosis: FDG-PET/CT Ratio Signals Malignancy in Branch-Duct IPMNs

In the realm of pancreatic branch-duct intraductal papillary mucinous neoplasms (bd-IPMNs), spotting malignancy is tricky. However, researchers delving into 58 cases discovered a game-changer. The standardized uptake value (SUV) from FDG-PET/CT, specifically the tumor-to-blood pool ratio (TBR), emerged as a potent indicator of malignancy. Correlating significantly with histopathology, TBR proved independently significant in scenarios defining high-grade dysplasia and invasive carcinoma or just invasive carcinoma. TBR might be the compass clinicians need for navigating malignant transformations in bd-IPMNs.