Examining 1404 Crohn’s disease patients post-ileocecal resection, researchers identified high-risk factors for surgical recurrence (multiple surgeries, active smoking, penetrating or perianal disease). Biologic prophylaxis post-surgery lowered surgical recurrence in high-risk patients. Additionally, prophylaxis reduced endoscopic recurrence regardless of risk, suggesting its potential benefits across risk profiles. These findings emphasize the relevance of individualized prophylactic approaches in postoperative Crohn’s disease management.
Journal Article by Shah RS, Bachour S (…) Click BH et 15 al. in Clin Gastroenterol Hepatol
Published by Elsevier Inc.