Improved Survival Associated with Resection in Localized Pancreatic Neuroendocrine Carcinoma

A retrospective study of 199 patients with localized small- and large-cell pancreatic neuroendocrine carcinoma (pannec) found that resection was associated with improved overall survival, while adjuvant chemotherapy did not significantly impact survival. The study also revealed an increasing trend in the rates of resection and adjuvant treatment since 2011. Resected patients were younger, treated more often at academic institutions, had more distal tumors, and a lower number of small-cell pannec. These findings highlight the potential benefit of resection in managing localized pannec, while suggesting the need for further investigation into the role of adjuvant chemotherapy.