Estimating the Rate of Low-Yield Surgery in Pancreatic Cancer Surveillance

The prevalence meta-analysis aimed to determine the rate of low-yield surgery in pancreatic cancer surveillance. A systematic search of relevant studies was conducted, including 5027 patients from 23 articles. The pooled prevalence of low-yield surgery was found to be 2.1%, with a slightly higher prevalence among familial pancreatic cancer subjects without known pathogenic variants. The overall prevalence of subjects under surveillance who had pancreatic resection with target lesions was 0.8%. The rate of low-yield surgeries decreased over time and stabilized at around 1%.