Researchers conducted a systematic review and meta-analysis comparing laparoscopic surgery (LS) to open surgery (OS) in patients with colorectal cancer. They found that LS resulted in milder proinflammatory reactions, as indicated by lower concentrations of inflammatory markers such as interleukins and C-reactive protein. The difference was particularly notable within the first 9 hours after surgery. These findings support the hypothesis that LS may have clinical benefits due to reduced operative trauma and its impact on humoral immunity.
Review by Bohne A, Grundler E (…) Fürst A et 2 al. in Surg Endosc
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