Extent of Surgery Found to Impact Gastrointestinal Function in Patients Undergoing CRS and HIPEC

This study investigated the impact of the extent of surgery on late adverse effects (LAEs) in patients undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). The study found that patients undergoing extensive CRS experienced persistent impaired gastrointestinal function in terms of diarrhea, compared to those undergoing less extensive surgery. However, the levels of other symptom scales significantly decreased from 3 to 12 months post-surgery. Clinicians should be attentive in detecting and addressing these LAEs in order to guide patients accordingly.