Enhanced Detection of the Recurrent Laryngeal Nerve Using Fluorescence Imaging during Thyroidectomy Procedures

Fluorescence imaging during thyroidectomy procedures significantly enhances the detection of the recurrent laryngeal nerve (RLN) with 100% sensitivity and specificity. All 81 RLNs observed were more clearly visualized under fluorescence compared to thyroid or background tissue. Fluorescence imaging also allowed for the visualization of all 30 RLNs and 45 nerve branches, whereas white light only visualized 17 RLNs and 22 nerve branches. In addition, visible nerve length was 2.5 times greater with fluorescence imaging.