Results from analyzing patients with high-risk T1 colorectal cancer who either received additional surgery or not after local excision (LE) showed that while regional lymph node metastasis was observed in the group that underwent additional surgery, the incidence of oncologic adverse events was significantly lower in the LE-alone group. The difference in 5-year cancer-specific survival was minimal between the two groups, but overall survival was significantly higher in the group that received additional surgery. This suggests that risk assessment is crucial in deciding whether to omit surgery for high-risk T1 tumors.
Journal Article by Ouchi A, Komori K (…) Ueno H et 30 al. in Ann Surg
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