Patients with lymph node distribution detected during laparoscopic colectomy with Japanese D3 dissection were divided into two groups: those with central vessel metastasis (LND3 group) and those without (LND1/2 group). After adjusting for background factors, the study found that LND3-positive patients had a worse prognosis compared to LND1/2 patients. Additionally, adjuvant chemotherapy improved the prognosis of LND3-positive patients. These findings suggest that lymph node distribution is an important prognostic indicator in colorectal cancer, and appropriate perioperative treatment strategies should be applied for LND3-positive patients.
Journal Article by Noda K, Tominaga T (…) Nagayasu T et 9 al. in Langenbecks Arch Surg
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