A propensity score matching study analyzed 220 colorectal cancer patients undergoing treatment in China. Prophylactic hyperthermic intraperitoneal chemotherapy (HIPEC) was associated with improved 3-year disease-free survival (DFS) compared to no HIPEC (HR 0.43). However, this benefit was not observed in patients with CT4N2M0 cancer. Laparoscopic surgery followed by HIPEC did not increase the risk of peritoneal metastasis. The study suggests that HIPEC may be an effective and safe curative treatment for selected patients with restricted peritoneal metastasis from colorectal cancer.
Journal Article by Zheng Y, Zhang J (…) Sun L et 11 al. in Eur J Surg Oncol
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