Organ-preserving pancreatectomy offers long-term advantages in endocrine and exocrine functions

Studies comparing organ-preserving pancreatectomy procedures have shown that central pancreatectomy (CP) leads to a lower incidence of new-onset or exacerbated diabetes compared to distal pancreatectomy (DP). However, CP is associated with increased morbidities such as pancreatic fistula. Spleen-preserving DP using the Kimura procedure reduces the risk of postoperative gastric varices and splenic infarction, but its effect on post-splenectomy infection prevention is unclear. Duodenum-preserving pancreatic head resection (DPPHR) has low postoperative cholangitis rates. While organ-preserving pancreatectomy may increase complications, it offers significant long-term advantages in endocrine and exocrine functions, suggesting wider adoption in the future.

Review by Kato H, Asano Y (…) Horiguchi A et 2 al. in Ann Gastroenterol Surg

© 2023 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterological Surgery.

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