Risk factors for anastomotic dehiscence in patients receiving negative pressure wound therapy after intestinal anastomosis.

The use of negative pressure wound therapy (NPWT) during intestinal anastomosis has been controversial. A single-center cohort study was conducted to identify risk factors for anastomotic dehiscence in patients who received NPWT therapy. The study found that females, delayed fascial closure, use of vasopressors, and NPWT pressures >110 mmHg were associated with a higher risk of anastomotic dehiscence. These findings suggest that caution should be exercised when using NPWT in patients undergoing intestinal anastomosis.