Patients achieving near-pathological complete response in locally advanced rectal cancer benefited from adjuvant chemotherapy, particularly those with ypt1-t2 stage tumors and positive lymph nodes. Act was associated with improved 5-year disease-free survival rates in downstage patients, emphasizing its significance in post-surgery outcomes. Additionally, serum carcinoembryonic antigen levels before treatment and ypT stage were identified as independent factors influencing survival outcomes in near-pcr patients.
Journal Article by Cai Y, Chen M (…) Kang L et 4 al. in Eur J Surg Oncol
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