Low Colorectal Cancer Risk After Resection of High-Risk Pedunculated Polyps

CRC incidence is significantly higher in patients with high-risk adenomas (HRAs) diagnosed at colonoscopy, with a 1.53-fold increase in risk. However, patients with only distal pedunculated polyps without high-grade dysplasia do not have an increased CRC risk. The presence of certain risk factors explains most of the excess CRC risk in the HRA group, indicating potential reduced burden of surveillance in FIT programs.