Histopathological Evaluation of Pouch Neoplasia Reveals the Importance of Annual Surveillance for High-Risk Patients

Neoplasia in the ileal pouch of patients with inflammatory bowel diseases or familial adenomatous polyposis is rare but poses a significant risk. Annual endoscopic surveillance is crucial for detecting dysplasia in high-risk patients. While dysplastic polyps in familial adenomatous polyposis are easily identifiable and removable, glandular dysplasia in ulcerative colitis may be challenging to detect. Adequate tissue sampling and expert histological analysis are recommended to accurately diagnose and manage neoplasia in the pouch and rectal cuff.