Preoperative chemoradiotherapy, but not chemotherapy, was found to be associated with a reduced risk of postoperative pancreatic fistula in patients undergoing pancreatoduodenectomy for pancreatic ductal adenocarcinoma. Out of the 2,019 patients included in the study, postoperative pancreatic fistula occurred in 8.3% after immediate surgery, 4.2% after preoperative chemotherapy, and 2.0% after preoperative chemoradiotherapy. These findings highlight the importance of considering preoperative chemoradiotherapy for reducing complications in pancreatic cancer surgery.
Journal Article by Wismans LV, Suurmeijer JA (…) van Eijck CHJ et 21 al. in BMC Surg
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