Cholecystectomy for uncomplicated cholelithiasis in sickle cell disease (SCD) patients leads to lower postoperative vaso-occlusive crises compared to those with acute cholecystitis, chronic cholecystitis, or gallstone pancreatitis. Advanced clinical presentations are strong predictors of complications, with 73% of SCD patients showing advanced clinical presentation at the time of cholecystectomy. These findings suggest that early cholecystectomy after screening with abdominal ultrasounds can improve outcomes in SCD patients with cholelithiasis.
Journal Article by Zeineddin A, Cornwell EE (…) Williams M et 5 al. in J Am Coll Surg
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