Centralization of Cytoreductive Surgery Alone Improves Perioperative Outcomes for Colorectal Peritoneal Metastases

Centralization of cytoreductive surgery alone for colorectal peritoneal metastases improved 90-day postoperative mortality and failure-to-rescue rates. High-volume centers showed lower mortality rates compared to low-volume and no-hipec centers. After the Prodige 7 trial, there was a drastic decrease in cytoreductive surgery with hyperthermic intraperitoneal chemotherapy rates in cancer centers, while patients treated with cytoreductive surgery alone continued to be referred to expert centers.