Maintained Quality of Life During Neoadjuvant Therapy for GI Cancers

QoL is maintained, with high symptom burden, during neoadjuvant therapy for gastrointestinal cancers. Functional well-being scores were consistently lower, while social well-being scores were higher. Common symptoms included fatigue, insomnia, and anxiety. Patients emphasized anxiety, fear, and frustration in free-text journaling but highlighted the importance of social support and confidence in healthcare providers.