Extent of Resection and Long-Term Outcomes for Appendiceal Adenocarcinoma
Mucinous and non-mucinous appendiceal adenocarcinomas exhibit differences in recurrence rates and nodal positivity. Colectomy is associated with improved disease-specific survival for non-mucinous tumors at certain stages and grades, but not for mucinous tumors. This suggests that colectomy may not be necessary for mucinous appendiceal adenocarcinoma patients.
In patients with gastric cancer and positive peritoneal lavage cytology or localized peritoneal metastasis, upfront chemotherapy followed by surgery yields better outcomes than surgery followed by chemotherapy.
Secondary cytoreductive surgery with hyperthermic intraperitoneal chemotherapy improves survival for select patients with recurrent colorectal cancer peritoneal metastases.