HPB & Spleen · 28 April 2024

Autologous Pancreatic Islet Cell Transplantation: Clinical Experience and Metabolic Outcomes

Autologous pancreatic islet cell transplantation (IAT) post-pancreatectomy is effective in preventing pancreatogenic diabetes. A 15-year study of the Milan Protocol shows sustained c-peptide secretion and optimal beta-cell function in patients, especially those who underwent partial pancreatectomy. IAT-related complications were observed in a small percentage of patients, with critical factors like the quantity of infused islets affecting metabolic outcomes.

Journal Article by Piemonti L, Melzi R (…) Balzano G et 14 al. in Transplantation

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