Diet and Antibiotics Impact Anastomotic Healing in Mice

Mouse study reveals that a high-fat-low-fiber diet leads to poor survival, weight loss, and reduced microbiome diversity compared to a low-fat-high-fiber diet. Pre-operative antibiotics enhance anastomotic healing by reducing enterococcus faecalis growth and improving collagen levels. Dietary fiber promotes post-operative recovery and microbiome biodiversity, highlighting the importance of diet and antibiotics in gut health and healing.