HPB & Spleen · 3 July 2024

Preoperative Chemotherapy Enables Resection in Advanced Pancreatic Cancer

Establishing preoperative chemotherapy (PCT) with FOLFIRINOX and gemcitabine/nab-paclitaxel enabled resectability in 61.2% of 139 patients with initially unresectable locally advanced pancreatic cancer. PCT did not increase perioperative mortality or morbidity, with 92.9% achieving R0 resection. Median postoperative survival was 31 months, highlighting the significant potential of PCT in extending recurrence-free and overall survival for resected patients.

Journal Article by Petrikowski M, Fahlbusch T (…) Belyaev O et 4 al. in Hepatobiliary Surg Nutr

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