A >50% decrease in intraoperative parathyroid hormone (iPTH) levels into the normal reference range predicts complete excision of malignancy in patients with parathyroid carcinoma. 93% of patients achieving normal iPTH levels had operative success, compared to only 50% of those with a >50% iPTH decrease alone. This study suggests that iPTH monitoring, particularly when guiding towards normal levels, can better predict successful removal of malignant tissue during surgery.
• Why it matters: The utility of iPTH monitoring for parathyroid carcinoma is unclear.
Journal Article by Armstrong VL, Vaghaiwalla TM (…) Lew JI et 5 al. in J Surg Res
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