In a multicentre cohort study involving 32,205 patients, two sequential preventive bundles led to a 50% reduction in surgical site infection rates, decreasing from 18.16% to 8.19%. Bundle-2 notably reduced both superficial and deep surgical site infections but was ineffective for organ/space infections in rectal surgery. Compliance with preventive measures improved with the addition of new protocols. Furthermore, length of hospital stay and mortality rates decreased significantly, suggesting enhanced patient outcomes.
Pragmatic Clinical Trial by Flores-Yelamos M, Gomila-Grange A (…) Juvany M et 7 al. in BJS Open
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