An analysis of 170 patients with acute cholecystitis revealed that 37.1% had gallbladder perforation, correlated with higher rates of complications. Key biomarkers, including C-reactive protein (CRP) and the CRP/albumin ratio (CAR), demonstrated significant differences between perforated and non-perforated cases. Despite their low specificity and sensitivity, these biomarkers can assist clinicians in making timely diagnoses and planning treatment strategies for this critical condition, potentially improving patient outcomes in high-risk situations.
Journal Article by Yalcin M, Tercan M, Ozyurt E and Baysan A in Ulus Travma Acil Cerrahi Derg