Negative-pressure wound therapy outperforms advanced moist wound therapy in diabetic foot ulcers

A randomized trial involving 450 participants demonstrated that negative-pressure wound therapy (NPWT) significantly outperformed advanced moist wound therapy in managing diabetic foot ulcers. Complete closure was achieved in 87% of NPWT recipients compared to just 29% for the moist therapy group. Additionally, NPWT resulted in a 48% reduction in wound size, lower infection rates, reduced recurrence, and fewer amputations. These results suggest NPWT as the superior choice for treating complex diabetic foot ulcers.