AI Model Enhances Prediction of Perineural Invasion in Pancreatic Cancer

An advanced AI model utilizing computed tomography can predict extrapancreatic perineural invasion (epni) in pancreatic ductal adenocarcinoma (PDAC) patients. Analyzing data from 1,065 patients, the model achieved an area under the curve of 0.87 to 0.83 across different validation sets. Furthermore, survival analysis confirmed significantly better outcomes for patients predicted to be epni-negative. With its robust diagnostic abilities, this AI tool could transform personalized treatment strategies in early PDAC.