Key factors predict failure to achieve textbook outcomes post-surgery

A systematic review and meta-analysis revealed five significant risk factors linked to failure in achieving textbook outcomes following pancreatoduodenectomy. Key contributors include preoperative biliary drainage, smaller tumor size, soft pancreatic texture, small pancreatic duct diameter, and increased intraoperative blood loss. These findings, synthesized from ten studies involving over 5,000 patients, aim to assist surgeons in identifying high-risk patients and enhancing surgical strategies and perioperative management to improve overall outcomes.