A recent systematic review and meta-analysis of 31 studies involving 17,968 participants demonstrated that triclosan-containing sutures substantially lower the incidence of surgical site infections compared to non-triclosan sutures, achieving a relative risk of 0.75 (95% CI, 0.65-0.86). Despite moderate certainty due to heterogeneity, the trial sequential analysis indicated that additional studies are unlikely to alter these findings. This evidence reinforces the clinical guideline recommendation for using triclosan sutures in surgical procedures.
Meta-Analysis by Jalalzadeh H, Timmer AS (…) Boermeester MA et 12 al. in JAMA Netw Open