EUS-TA significantly enhances diagnostic accuracy for biliary lesions

Endoscopic ultrasound-guided tissue acquisition (EUS-TA) demonstrated high diagnostic yields in biliary lesions, achieving 96.3% sensitivity and 100% specificity. Of 71 cases, 54 were diagnosed as malignant, marking a 76.1% malignancy rate. When combined with endoscopic retrograde cholangiography (ERC), EUS-TA increased overall diagnostic accuracy from 82.5% to 94.2%, identifying 30 additional malignant cases. The procedure’s adverse event rate was low, with only one case of peritonitis reported.