A novel preoperative model for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC) has been developed based on key clinical characteristics and serum biomarkers. Analyzing 1,027 patient cases, independent risk factors identified include hepatitis B virus infection, tumor size, and several alpha-fetoprotein markers. The model demonstrated strong diagnostic performance, with AUC values of 0.806 and 0.818 in development and validation cohorts, respectively, ensuring consistency with postoperative outcomes and promising clinical applicability.
Validation Study by Wang XQ, Fan YQ (…) Si YQ et 3 al. in J Invest Surg