Evaluation of total metastases volume (TMV) and relative volume reduction (RVR) reveals their superior predictive ability over established clinical risk scores (CRS) for colorectal liver metastases post-neoadjuvant chemotherapy. Patients with TMV below 29.5 ml before and 7.5 ml after therapy had significantly longer progression-free survival (PFS) and overall survival (OS). An RVR of at least 73% also demonstrated considerable positive impact on both PFS and OS compared to lower reductions.
Journal Article by Lindenlaub F, Asenbaum U (…) Kaczirek K et 4 al. in Ann Surg Oncol
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