Treatment adjustments significantly enhance endoscopic prognosis in Crohn’s disease

In a cohort of 199 Crohn’s disease patients with postoperative anastomotic lesions, treatment adjustments yielded notable improvements in endoscopic outcomes. Specifically, strategies such as biologics switching and biologic optimization led to marked mucosal healing and ulcer improvement. Switching from non-biologics to biologics resulted in superior endoscopic results, while optimization of biologics enhanced outcomes for patients with low trough levels. Overall, these findings emphasize the effectiveness of tailored treatment adjustments in improving patient prognosis.