A critical study found that pre-treatment fibrinogen levels below 1.3 g/l indicate poor prognosis in patients with major bleeding. Among 7,063 patients analyzed, those with fibrinogen above this threshold experienced a significant survival benefit after 28 days. Furthermore, a post-treatment fibrinogen target of 2.0-2.5 g/l was identified as optimal for enhancing survival rates. These findings suggest the importance of monitoring and managing fibrinogen levels in critically bleeding patients to improve ICU outcomes.
Journal Article by Ren B, Zhang Y (…) Chang Z et 3 al. in Eur J Trauma Emerg Surg
© 2025. The Author(s).