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Intestine and Lower Gastrointestinal Tract ·

Neoadjuvant treatment leads to promising watch and wait outcomes in rectal cancer

A nationwide study reveals that 15% of patients with non-metastasized rectal cancer successfully utilized a watch and wait strategy after neoadjuvant treatment. Among those treated with chemoradiotherapy, 21% achieved favorable results, compared to just 7% for short-course radiotherapy. Organ preservation rates improved to 17% when local excisions were included. Data indicate better baseline performance and lower tumor stages in patients opting for watch and wait, with three-year survival rates of 81% for short-course and 95% for chemoradiotherapy groups.

Journal Article by Mens DM, Coebergh van den Braak RRJ (…) Olthof PB et 10 al. in Eur J Surg Oncol

Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.

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