Endoscopic techniques improve outcomes for rectal precancerous lesions.

Innovative endoscopic procedures, including endoscopic submucosal dissection (ESD) and full-thickness resection, significantly enhance treatment for widespread precancerous lesions and early rectal cancers. ESD achieves over 90% R0 resection rates and offers a low recurrence risk of 3%. Notably, lesions up to 20 cm can be resected in one piece. These advancements allow thorough histopathologic analysis, particularly vital for T1 cancers, facilitating enhanced patient outcomes and addressing challenges in treating complex colorectal conditions.