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Intestine and Lower Gastrointestinal Tract ·

Size cut-offs established for rectal neuroendocrine neoplasm recurrence

A recent retrospective study involving 1,011 patients identified critical size thresholds for rectal neuroendocrine neoplasms (NENs). For grade 1 tumors, a 0.7 cm cut-off showed 100% sensitivity and 79% specificity, indicating minimal recurrence risk. Conversely, grade 1 tumors with lymphovascular invasion necessitated a 1.5 cm cut-off. Grade 2 NENs, which exhibited a 22.9% lymph node metastasis rate, require continual surveillance regardless of size. These insights aim to refine follow-up strategies for improved patient management.

Journal Article by Kim S, Kim ER (…) Cho YB et 9 al. in Dig Endosc

© 2025 The Author(s). Digestive Endoscopy published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society.

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