High allostatic load (AL) significantly correlates with increased risks of complications in colorectal cancer (CRC) surgeries. Among over 40,000 patients, those with high AL had a 48% greater likelihood of postoperative complications, a 79% increased chance of prolonged hospital stays, and doubled mortality risk within 30 days post-surgery. The study emphasizes that CRC patients from socially vulnerable neighborhoods suffer additional physiological damage, highlighting the necessity for preoperative screenings to address these disparities.
Journal Article by Khalil M, Woldesenbet S (…) Pawlik TM et 7 al. in Ann Surg Oncol
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