New model accurately predicts lymph node metastases in surgery

A predictive model for lymph node metastases (lnm) in intrahepatic cholangiocarcinoma patients undergoing adequate lymphadenectomy has been developed, revealing significant associations with preoperative CA 19-9 levels, suspicious lymph nodes, patient age, and tumor burden score. Analysis of 693 patients resulted in a model with high predictive accuracy, demonstrated by c-statistics of 0.723 and 0.771 in derivation and validation cohorts, respectively. Risk categories indicated increasing lnm rates from 29.9% to 87.3% across risk groups.