Positive lymph node ratio enhances prognosis in colorectal cancer

A prognostic model incorporating positive lymph node ratio (LNR) significantly improves disease-free survival (DFS) predictions in yp stage III colorectal cancer patients post-neoadjuvant therapy. An optimal LNR threshold of 0.29 highlighted its role as an independent prognostic factor, with high LNR correlating to shorter DFS rates (HR=2.103). Furthermore, a nomogram integrating LNR demonstrated superior predictive power compared to conventional TNM staging (AUC: 0.852 vs. 0.781, p<0.05), underscoring its clinical relevance for patient prognosis.

Journal Article by Xia K, Wang L and Tang N in Updates Surg

© 2025. Italian Society of Surgery (SIC).

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