A systematic review has led to updated clinical guidelines for inhospital coagulation management and fluid replacement therapy in patients with severe injuries. Key recommendations stress the importance of early interventions for trauma-induced coagulopathy and the use of viscoelastic assays to guide treatment. Notably, tranexamic acid should not be universally applied in emergency situations, as only 20% of trauma patients display hyperfibrinolysis. The updated guidelines are derived from the evidence of fifty-nine new studies, improving consensus in clinical practice.
Systematic Review by Lier H, Goossen K (…) Hilbert-Carius P et 4 al. in Eur J Trauma Emerg Surg
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