The PANDRA II trial revealed that patients undergoing left pancreatectomy without routine abdominal drainage had similar morbidity rates compared to those with drainage. The no-drain group demonstrated noninferiority in overall postoperative morbidity, with a comprehensive complication index of 13.90 versus 19.43 for the drain group (p < 0.001). Additionally, the no-drain approach resulted in a significant reduction in overall complication rates (50.41% vs 78.40%, p < 0.001). Specific complications remained comparable.
Randomized Controlled Trial by Kaiser J, Niesen W (…) Probst P et 13 al. in Ann Surg
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