New model predicts pancreatic fistula risk after surgery

A predictive model for clinically relevant postoperative pancreatic fistula (cr-popf) was developed, showing a 29.1% occurrence rate among trained patients. Utilizing postoperative day 5 C-reactive protein and drain fluid amylase levels, the model achieved area under the ROC curves of 0.787 and 0.750, respectively. This index, validated through additional cohorts, assists surgeons in assessing risk and determining safe early drain removal, enhancing postoperative care following pancreaticoduodenectomy.