Advancements in massive transfusion protocols (MTPs) highlight the importance of balanced transfusion strategies, utilizing a 1:1:1 ratio of plasma, platelets, and red blood cells. This approach significantly enhances early hemorrhage control, though challenges persist with individual patient variability. Viscoelastic hemostatic assays facilitate personalized treatment by providing real-time clot assessments. Renewed interest in whole blood transfusions, informed by military practices, offers logistical advantages and survival benefits, prompting calls for refined protocols and precision medicine to optimize patient outcomes.
Review by Lin TL, Liu HT and Hsieh CH in J Formos Med Assoc
Copyright © 2025 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.