Evidence from a comprehensive meta-analysis reveals that surgical intervention dramatically outperforms nonsurgical management for pancreatic neuroendocrine tumors. With a pooled hazard ratio for mortality of 0.30, surgical patients showed better survival rates at one, three, five, and ten years compared to their nonsurgical counterparts. While surgical options are paramount for resectable tumors, nonsurgical management remains viable for select cases of small, asymptomatic tumors less than 1 cm.
Review by Khajeh E, Shahrbaf M (…) Mehrabi A et 3 al. in Ann Surg Oncol
© 2025. The Author(s).